Differences between innate host defense and acquired immunity

Innate and acquired arms of immunity work together, as an integrated immune system, to protect us against infections by pathogenic microbes. Interestingly, innate and acquired immune systems have some differences. We shall highlight these differences under the following headings: Speed of response and potency of response Specificity of response Immunological memory Cellular mediators Components Overview […]

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Antimicrobial proteins that enhance innate defense

In our last lecture, we studied phagocytosis as a component of innate host defense. In today’s lecture, we shall study various antimicrobial proteins (enzymes inclusive), in blood and tissue fluids, that provide the body with innate defenses against pathogenic microbes. The body produces these enzymes and proteins at any given time and they mostly circulate […]

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Innate Defense Mechanisms I

Innate defense mechanisms of the humans against microbes are carried out by different ways Anatomical barriers, Physiological barriers, Inflammatory mechanism, Phagocytic mechanism, Enzyme and soluble proteins of the innate immune system. ANATOMICAL BARRIERS Skin, cornea and mucus membrane lining the respiratory tract, digestive tract, and genitourinary tracts act as mechanical barriers and prevent the entry […]

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Basic concepts in Modern Immunology

Immunology is the study of the various mechanisms of host defenses against infections, infectious diseases and neoplasm, together with the undesirable consequences of immune interactions such as inflammation, autoimmunity, and hypersensitivity reactions. Pathogens are organisms that invade our body to cause disease. They are five types of human pathogens; Bacteria Fungi Viruses Protozoa Worms (helminthes) […]

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